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Celebration of Scholars

 

Additional Information

More information is available at carthage.edu/celebration-scholars/. The following are members of the Research, Scholarship, and Creativity Committee who are eager to listen to ideas and answer questions:

  • Thomas Carr
  • Katherin Hilson
  • Kim Instenes
  • John Kirk
  • Sarah Terrill

Apoptosis: A Target for Anticancer Therapy

Name: Claire Pfeffer
Major: Biology
Hometown: Oregon, WI
Faculty Sponsor: Amareshwar Singh
Other Sponsors:  
Type of research: Independent research

Abstract

Apoptosis, the cell’s natural mechanism for death, is a promising target for anticancer therapy. Both the intrinsic and extrinsic pathways use caspases to carry out apoptosis through the cleavage of hundreds of proteins. In cancer, the apoptotic pathway is typically inhibited through a wide variety of means including overexpression of antiapoptotic proteins and under-expression of proapoptotic proteins. Many of these changes cause intrinsic resistance to the most common anticancer therapy, chemotherapy. Promising new anticancer therapies are plant-derived compounds that exhibit anticancer activity through activating the apoptotic pathway.

Poster file

Submit date: March 27, 2018, 11:37 a.m.

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