Conducting Micelle-Assisted Peptide Coupling in Flow — Presentation Detail — Celebration of Scholars

Instructions

Student presentations must have a faculty sponsor.

Abstracts must include a title and a description of the research, scholarship, or creative work. The description should be 150-225 words in length and constructed in a format or style appropriate for the presenter’s discipline.

The following points should be addressed within the selected format or style for the abstract:

A clear statement of the problem or question you pursued, or the scholarly goal or creative theme achieved in your work.
A brief comment about the significance or uniqueness of the work.
A clear description of the methods used to achieve the purpose or goals for the work.
A statement of the conclusions, results, outcomes, or recommendations, or if the work is still in progress, the results you expect to report at the event.

Presenter photographs should be head and shoulder shots comparable to passport photos.

Additional Information

More information is available at carthage.edu/celebration-scholars/. The following are members of the Research, Scholarship, and Creativity Committee who are eager to listen to ideas and answer questions:

Jun Wang
Kim Instenes
John Kirk
Nora Nickels
Andrew Pustina
James Ripley

Conducting Micelle-Assisted Peptide Coupling in Flow

Name: Gunnar Goetz
Major: Chemistry
Hometown: Lindenhurst, IL
Faculty Sponsor: David Brownholland
Other Sponsors:
Type of research: Independent research
Funding: Carthage Undergraduate Research Grant

Name: Gunnar Goetz
Major: Chemistry
Hometown: Stoughton, WI
Faculty Sponsor: David Brownholland
Other Sponsors:
Type of research: Independent research
Funding: Carthage Undergraduate Research Grant

Abstract

Micelle-facilitated reactions are receiving significant attention due to their potential to remove toxic organic solvents from organic reactions in favor of water. These reactions often produce equivalent or superior results compared to their analogous reactions in organic solvent. Furthermore, micelle-facilitated reactions can often be conducted at room temperature with shorter reaction times, offering significant environmental and practical advantages. Despite growing interest, micelle-facilitated organic synthesis has yet to be adapted for flow conditions. Continuous-flow synthetic processes offer advantages over batch reactions, such as improved heat transfer and the ability to increase pressure and temperature safely above the boiling point of the solvent, thus enabling faster reactions. These benefits enable quick screening of reaction conditions. Further, flow chemistry is easily scalable, either through collecting a sample for longer periods of time or through running reactions in parallel. In addition to the benefits to traditional research, flow chemistry is recognized as necessary to conduct extraterrestrial chemical research. We report our progress on a peptide coupling reaction in aqueous flow conditions using micellar catalysts.

Poster file