Celebration of Scholars
Development of Human Escape/Avoidance Task Using Transdermal Stimulation As An Unconditioned Stimulus
Name:
Kevin Dunn
Major: Biology
Hometown: Madison, WI
Faculty Sponsor:
Paul Martino
Other Sponsors: Daniel Miller, Denise Cook-Snyder, Justin Miller
Type of research: Course project
Name:
Alexandra Arber
Major: Neuroscience, Psychology
Hometown: McHenry, IL
Faculty Sponsor:
Paul Martino
Other Sponsors: Daniel Miller, Justin Miller, Denise Cook-Snyder
Type of research: Course project
Abstract
Behavioral inhibition (BI) is believed to be a genetically determined trait that affects about 33% of the population. These individuals tend to respond to stressful situations differently than non-behaviorally inhibited (non-BI) individuals. Research has shown significant behavioral differences between strains of Wistar-Kyoto rats with behaviorally inhibited and non-behaviorally inhibited genetic predispositions. Among this pool of research, differences have been observed in avoidance behaviors between BI and non-BI rats. Our laboratory has recently published a manuscript describing how the parasympathetic nervous system in college age BI females is underactive, potentially being part of the physiological reason for their increased anxiety and response to stressful stimuli. In a future study, we will use transdermal stimulation as an environmental stressor and observe how participants respond to the unknown administration of transdermal stimulation with the opportunity to avoid the stressor or escape it. As part of laboratory-based assignment, we students attempted to determine appropriate low, medium, and high intensities for transdermal stimulation to be used as a stimulus in a future escape/avoidance study. Eight transdermal stimulations of varying magnitude were delivered in a random order between 30-100 mV in intervals of 10 mV for each participant. Participants were asked to rate the stimulation intensity levels, ranging from 1 (barely perceptible) to 10 (extremely perceptible). We determined that the low level of stimulation would be 50 mV with a 3.75 +/- 1.53, a medium level of 70 mV with a 6.38 +/- 1.31, and a high level of 90 mV with a 7.38 +/- 1.54 intensity rating. These intensity values will provide a range that can be tested when paired with neutral stimuli to induce escape/avoidance behavior.